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Term Information

Accession
GO:0002460
Name
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus. Source: ISBN:0781735149, GOC:mtg_sensu, GOC:add, ISBN:1405196831
Comment
None
History
See term history for GO:0002460 at QuickGO
Subset
None
Feedback
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Graph of GO:0002460

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Parents of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002460)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [is_a relation] is_a  adaptive immune response (GO:0002250)
Children of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002460)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
tolerance induction dependent upon immune response (GO:0002461) [is_a relation] is_a  adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
primary adaptive immune response involving T cells and B cells (GO:0090721) [is_a relation] is_a  adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002824) [RO:0002213 relation] RO:0002213  adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
adaptive immune memory response involving T cells and B cells (GO:0090717) [is_a relation] is_a  adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
T-helper 1 type immune response (GO:0042088) [is_a relation] is_a  adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
germinal center formation (GO:0002467) [is_a relation] is_a  adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002823) [RO:0002212 relation] RO:0002212  adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002822) [RO:0002211 relation] RO:0002211  adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
T-helper 17 type immune response (GO:0072538) [is_a relation] is_a  adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
adaptive immune effector response involving T cells and B lineage cells (GO:0090719) [is_a relation] is_a  adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
T cell mediated immunity (GO:0002456) [is_a relation] is_a  adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
B cell mediated immunity (GO:0019724) [is_a relation] is_a  adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
None.