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immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor

Term Information

Accession
GO:0002415
Name
immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor
Ontology
biological_process
Synonyms
antibody transcytosis mediated by pIgR, immunoglobulin transcytosis mediated by pIgR
Alternate IDs
None
Definition
The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa. Source: ISBN:0781735149, GOC:add, ISBN:081533642X, PMID:16048543
Comment
None
History
See term history for GO:0002415 at QuickGO
Subset
None
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Graph of GO:0002415

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Parents of immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor (GO:0002415)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [BFO:0000050 relation] BFO:0000050  mucosal immune response (GO:0002385)
immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [is_a relation] is_a  immunoglobulin transcytosis in epithelial cells (GO:0002414)

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