Planteome: Term Details for "plasma kallikrein-kinin cascade" (GO:0002353)

Accession: GO:0002353
Name: plasma kallikrein-kinin cascade
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: A series of reactions that takes place outside the cell occurring in response to tissue damage and initiated within blood plasma by the action of activated Factor XII (Hageman Factor) on prekallikrein to convert it to plasma kallikrein, and the subsequent reaction of plasma kallikrein with high molecular weight kininogen. The ultimate product of the plasma kallikrein-kinin cascade is bradykinin, an agent known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability. Source: PMID:11842287, PMID:14501145, GOC:add, ISBN:0721601871
Comment: None
History: See term history for GO:0002353 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to plasma kallikrein-kinin cascade.; Link to all direct and indirect annotations to plasma kallikrein-kinin cascade.; Link to all direct and indirect annotations download (limited to first 10,000) for plasma kallikrein-kinin cascade.
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subject	relation	object
plasma kallikrein-kinin cascade	is_a	kinin cascade (GO:0002254)

subject	relation	object
positive regulation of plasma kallikrein-kinin cascade (GO:0002550)	RO:0002213	plasma kallikrein-kinin cascade
Factor XII activation (GO:0002542)	BFO:0000050	plasma kallikrein-kinin cascade
negative regulation of plasma kallikrein-kinin cascade (GO:0002549)	RO:0002212	plasma kallikrein-kinin cascade
regulation of plasma kallikrein-kinin cascade (GO:0002529)	RO:0002211	plasma kallikrein-kinin cascade

plasma kallikrein-kinin cascade