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Term Information

Accession
GO:0002344
Name
B cell affinity maturation
Ontology
biological_process
Synonyms
B lymphocyte affinity maturation, B-cell affinity maturation, B-lymphocyte affinity maturation
Alternate IDs
None
Definition
The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen. Source: ISBN:0781735149, GO_REF:0000022, GOC:jal
Comment
None
History
See term history for GO:0002344 at QuickGO
Subset
None
Feedback
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Graph of GO:0002344

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Parents of B cell affinity maturation (GO:0002344)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
B cell affinity maturation [BFO:0000050 relation] BFO:0000050  immunoglobulin production involved in immunoglobulin-mediated immune response (GO:0002381)
B cell affinity maturation [is_a relation] is_a  peripheral B cell selection (GO:0002343)
Children of B cell affinity maturation (GO:0002344)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
somatic hypermutation of immunoglobulin genes involved in immune response (GO:0002205) [BFO:0000050 relation] BFO:0000050  B cell affinity maturation
None.