Planteome: Term Details for "podosome" (GO:0002102)

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Term Information

Accession: GO:0002102
Name: podosome
Ontology: cellular_component
Synonyms: None
Alternate IDs: None
Definition: An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm. Source: PMID:15890982, PMID:12837608
Comment: Note that podosomes can be distinguished from other F-actin-rich structures or from other matrix contacts. For example, focal adhesions and focal contacts do not display a core structure of F-actin. Unlike focal adhesions, podosome assembly does not require de novo protein synthesis. However, most of the podosome ring components are found in focal adhesions and other cell-matrix contacts. Podosomes are typically found in cells that cross tissue boundaries, recruited to the leading edge of migrating cells, and are often sites of extracellular matrix degradation.
History: See term history for GO:0002102 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to podosome.; Link to all direct and indirect annotations to podosome.; Link to all direct and indirect annotations download (limited to first 10,000) for podosome.
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GO:0005575 cellular_component
GO:0110165 cellular anatomical entity
GO:0005622 intracellular anatomical structure
GO:0043232 intracellular non-membrane-bounded organelle
GO:0043226 organelle
GO:0005856 cytoskeleton
GO:0043229 intracellular organelle
GO:0043228 non-membrane-bounded organelle
GO:0015629 actin cytoskeleton
GO:0002102 podosome
GO:0061825 podosome core
GO:0061826 podosome ring

Parents of podosome (GO:0002102)

subject	relation	object
podosome	BFO:0000050	actin cytoskeleton (GO:0015629)
podosome	is_a	intracellular non-membrane-bounded organelle (GO:0043232)

Children of podosome (GO:0002102)

subject	relation	object
podosome ring (GO:0061826)	BFO:0000050	podosome
podosome core (GO:0061825)	BFO:0000050	podosome

Wikipedia: Podosome