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Term Information

Accession
GO:0001837
Name
epithelial to mesenchymal transition
Ontology
biological_process
Synonyms
EMT, epithelial-mesenchymal transition, mesenchymal cell differentiation from epithelial cell
Alternate IDs
None
Definition
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Source: GOC:dph, PMID:14701881
Comment
None
History
See term history for GO:0001837 at QuickGO
Subset
None
Feedback
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Graph of GO:0001837

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Parents of epithelial to mesenchymal transition (GO:0001837)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
epithelial to mesenchymal transition [is_a relation] is_a  mesenchymal cell differentiation (GO:0048762)
Children of epithelial to mesenchymal transition (GO:0001837)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of epithelial to mesenchymal transition (GO:0010717) [RO:0002211 relation] RO:0002211  epithelial to mesenchymal transition
clearance of cells from fusion plate by epithelial to mesenchymal transition (GO:0060886) [is_a relation] is_a  epithelial to mesenchymal transition
mesodermal to mesenchymal transition involved in gastrulation (GO:0060809) [is_a relation] is_a  epithelial to mesenchymal transition
negative regulation of epithelial to mesenchymal transition (GO:0010719) [RO:0002212 relation] RO:0002212  epithelial to mesenchymal transition
positive regulation of epithelial to mesenchymal transition (GO:0010718) [RO:0002213 relation] RO:0002213  epithelial to mesenchymal transition
cardiac epithelial to mesenchymal transition (GO:0060317) [is_a relation] is_a  epithelial to mesenchymal transition
epicardial cell to mesenchymal cell transition (GO:0003347) [is_a relation] is_a  epithelial to mesenchymal transition
neural crest formation (GO:0014029) [is_a relation] is_a  epithelial to mesenchymal transition
None.