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Term Information

Accession
GO:0001228
Name
DNA-binding transcription activator activity, RNA polymerase II-specific
Ontology
molecular_function
Synonyms
RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II transcriptional activator activity, copper ion regulated proximal promoter sequence-specific DNA binding, RNA polymerase II transcriptional activator activity, metal ion regulated core promoter proximal region sequence-specific binding, RNA polymerase II transcriptional activator activity, metal ion regulated proximal promoter sequence-specific DNA binding, RNA polymerase II transcriptional activator activity, zinc ion regulated core promoter proximal region sequence-specific binding, RNA polymerase II transcriptional activator activity, zinc ion regulated proximal promoter sequence-specific DNA binding, copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription, distal enhancer DNA-binding transcription activator activity, RNA polymerase II-specific, metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription, metal ion regulated sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific, sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in positive regulation of transcription, transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding, transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding, transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding, transcriptional activator activity, metal ion regulated sequence-specific DNA binding, zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription
Alternate IDs
GO:0001209, GO:0001205, GO:0001212, GO:0001213, GO:0001211, GO:0001077
Definition
Interacting selectively and non-covalently with a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units. Source: GOC:txnOH-2018, PMID:27145859, PMID:20737563, GOC:aruk
Comment
None
History
See term history for GO:0001228 at QuickGO
Subset
None
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Parents of DNA-binding transcription activator activity, RNA polymerase II-specific (GO:0001228)
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DNA-binding transcription activator activity, RNA polymerase II-specific [is_a relation] is_a  DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)
DNA-binding transcription activator activity, RNA polymerase II-specific [is_a relation] is_a  DNA-binding transcription activator activity (GO:0001216)
DNA-binding transcription activator activity, RNA polymerase II-specific [BFO:0000050 relation] BFO:0000050  positive regulation of transcription by RNA polymerase II (GO:0045944)

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