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Term Information

Accession
GO:0001227
Name
DNA-binding transcription repressor activity, RNA polymerase II-specific
Ontology
molecular_function
Synonyms
RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II transcriptional repressor activity, metal ion regulated core promoter proximal region sequence-specific binding, RNA polymerase II transcriptional repressor activity, metal ion regulated proximal promoter sequence-specific DNA binding, distal enhancer DNA-binding transcription repressor activity, RNA polymerase II-specific, metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in negative regulation of transcription, metal ion regulated sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific, sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in negative regulation of transcription, transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding, transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding, transcriptional repressor activity, metal ion regulated sequence-specific DNA binding
Alternate IDs
GO:0001206, GO:0001214, GO:0001210, GO:0001078
Definition
A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II. Source: GOC:txnOH-2018
Comment
For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.
History
See term history for GO:0001227 at QuickGO
Subset
None
Feedback
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Graph of GO:0001227

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Parents of DNA-binding transcription repressor activity, RNA polymerase II-specific (GO:0001227)
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DNA-binding transcription repressor activity, RNA polymerase II-specific [BFO:0000050 relation] BFO:0000050  negative regulation of transcription by RNA polymerase II (GO:0000122)
DNA-binding transcription repressor activity, RNA polymerase II-specific [BFO:0000051 relation] BFO:0000051  RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977)
DNA-binding transcription repressor activity, RNA polymerase II-specific [is_a relation] is_a  DNA-binding transcription repressor activity (GO:0001217)
DNA-binding transcription repressor activity, RNA polymerase II-specific [is_a relation] is_a  DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)

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