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Term Information

Accession
GO:0000724
Name
double-strand break repair via homologous recombination
Ontology
biological_process
Synonyms
HDR, HRR, Rad51-dependent recombinational repair, Rhp51-dependent recombinational repair, homologous recombinational repair, homology-directed repair
Alternate IDs
GO:0016924
Definition
The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule. Source: GOC:elh, PMID:10357855
Comment
None
History
See term history for GO:0000724 at QuickGO
Subset
None
Feedback
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Graph of GO:0000724

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Parents of double-strand break repair via homologous recombination (GO:0000724)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
double-strand break repair via homologous recombination [is_a relation] is_a  double-strand break repair (GO:0006302)
double-strand break repair via homologous recombination [is_a relation] is_a  recombinational repair (GO:0000725)
Children of double-strand break repair via homologous recombination (GO:0000724)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
double-strand break repair via synthesis-dependent strand annealing (GO:0045003) [is_a relation] is_a  double-strand break repair via homologous recombination
DNA synthesis involved in double-strand break repair via homologous recombination (GO:0043150) [BFO:0000050 relation] BFO:0000050  double-strand break repair via homologous recombination
double-strand break repair via break-induced replication (GO:0000727) [is_a relation] is_a  double-strand break repair via homologous recombination
positive regulation of double-strand break repair via homologous recombination (GO:1905168) [RO:0002213 relation] RO:0002213  double-strand break repair via homologous recombination
negative regulation of double-strand break repair via homologous recombination (GO:2000042) [RO:0002212 relation] RO:0002212  double-strand break repair via homologous recombination
replication-born double-strand break repair via sister chromatid exchange (GO:1990414) [is_a relation] is_a  double-strand break repair via homologous recombination
regulation of double-strand break repair via homologous recombination (GO:0010569) [RO:0002211 relation] RO:0002211  double-strand break repair via homologous recombination
None.