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Term Information

Accession
GO:0000388
Name
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
Ontology
biological_process
Synonyms
U12-type spliceosome conformational change to release U4atac and U11, U2-type spliceosome conformational change to release U4 and U1, spliceosomal A1 complex biosynthesis, spliceosomal A1 complex formation, spliceosomal B2 complex biosynthesis, spliceosomal B2 complex formation, 3'-splice site cleavage, exon ligation
Alternate IDs
GO:0000396, GO:0000397
Definition
Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11). Source: GOC:krc, ISBN:0879695897
Comment
Note that this step represents formation of the A1 complex (yeast) or the B2 complex (mammalian).
History
See term history for GO:0000388 at QuickGO
Subset
None
Feedback
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Graph of GO:0000388

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Parents of spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) (GO:0000388)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [is_a relation] is_a  ribonucleoprotein complex assembly (GO:0022618)
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [BFO:0000050 relation] BFO:0000050  spliceosomal conformational changes to generate catalytic conformation (GO:0000393)

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